CNOT1 antibody (AA 595-744) (HRP)

Catalog No. ABIN7147096

This anti-CNOT1 antibody is a Rabbit Polyclonal antibody detecting CNOT1 in ELISA. Suitable for Human.

Quick Overview for CNOT1 antibody (AA 595-744) (HRP) (ABIN7147096)

Target: CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-CNOT1 Antibody (HRP)

Binding Specificity: AA 595-744

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 10 protein (595-744AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CNOT1

Target: CNOT1 (CCR4-NOT Transcription Complex, Subunit 1 (CNOT1))

Alternative Name: CNOT1

Background:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.

Aliases: CNOT10CCR4-NOT transcription complex subunit 10 antibody

UniProt: Q9H9A5

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Stem Cell Maintenance