CD2AP antibody (AA 333-426)

Catalog No. ABIN7147135

This anti-CD2AP antibody is a Rabbit Polyclonal antibody detecting CD2AP in WB, ELISA, IHC and IF. Suitable for Human.

Quick Overview for CD2AP antibody (AA 333-426) (ABIN7147135)

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD2AP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD2AP Antibody

Binding Specificity: AA 333-426

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CD2-associated protein (333-426AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Alternative Name: CD2AP

Background:

Background: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.

Aliases: Adapter protein CMS antibody, AL024079 antibody, C78928 antibody, Cas ligand with multiple SH3 domains antibody, CD2 associated protein antibody, CD2-associated protein antibody, CD2AP antibody, CD2AP_HUMAN antibody, CMS antibody, Mesenchyme to epithelium transition protein with SH3 domains 1 antibody, METS 1 antibody, Mets1 antibody

UniProt: Q9Y5K6