CD276 antibody (AA 29-200)

Catalog No. ABIN7147148

This Rabbit Polyclonal antibody specifically detects CD276 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CD276 antibody (AA 29-200) (ABIN7147148)

Target: CD276

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD276 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CD276 Antibody

Binding Specificity: AA 29-200

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human CD276 antigen protein (29-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD276

Target: CD276

Alternative Name: CD276

Background:

Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Aliases: 4Ig B7 H3 antibody, 4Ig-B7-H3 antibody, AU016588 antibody, B7 H3 antibody, B7 homolog 3 antibody, B7-H3 antibody, B7H3 antibody, B7RP-2 antibody, CD_antigen=CD276 antibody, CD276 antibody, CD276 antigen antibody, CD276 Molecule antibody, CD276_HUMAN antibody, Costimulatory molecule antibody, Flags: Precursor antibody, PSEC0249 antibody, UNQ309/PRO352 antibody

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints