MEF2D antibody (pSer180) (Biotin)

Catalog No. ABIN710503

This Rabbit Polyclonal antibody specifically detects MEF2D in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for MEF2D antibody (pSer180) (Biotin) (ABIN710503)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2D antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MEF2D Antibody (Biotin)

Binding Specificity: pSer180

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser180

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D

Background:

Synonyms: MEF2Dphospho S180, MADS box transcription factor 2 polypeptide D, Mef2d, MEF2D_HUMAN, y myocyte enhancer factor 2D, Myocyte specic enhancer factor 2D, myocyte-specic enhancer factor 2D.

Background: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.

Gene ID: 4209