CIDEA antibody (AA 1-51)

Catalog No. ABIN7147273

This anti-CIDEA antibody is a Rabbit Polyclonal antibody detecting CIDEA in WB, ELISA, IHC and IF. Suitable for Human.

Quick Overview for CIDEA antibody (AA 1-51) (ABIN7147273)

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIDEA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CIDEA Antibody

Binding Specificity: AA 1-51

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell death activator CIDE-A protein (1-51AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Alternative Name: CIDEA

Background:

Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

Aliases: CIDEACell death activator CIDE-A antibody, Cell death-inducing DFFA-like effector A antibody

UniProt: O60543