CCAR1 antibody (AA 1-200)

Catalog No. ABIN7147295

This Rabbit Polyclonal antibody specifically detects CCAR1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CCAR1 antibody (AA 1-200) (ABIN7147295)

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CCAR1 Antibody

Binding Specificity: AA 1-200

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cell division cycle and apoptosis regulator protein 1 protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Alternative Name: CCAR1

Background:

Background: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.

Aliases: CARP-1 antibody, Carp1 antibody, Ccar1 antibody, CCAR1_HUMAN antibody, Cell cycle and apoptosis regulatory protein 1 antibody, cell division cycle and apoptosis regulator 1 antibody, Cell division cycle and apoptosis regulator protein 1 antibody, Death inducer with SAP domain antibody, FLJ10590 antibody, FLJ10839 antibody, FLJ13376 antibody, FLJ20734 antibody, MGC7730 antibody, RP11-437A18.1 antibody

UniProt: Q8IX12