TMEM2 antibody (AA 734-866) (Biotin)

Catalog No. ABIN7147331

This Rabbit Polyclonal antibody specifically detects TMEM2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TMEM2 antibody (AA 734-866) (Biotin) (ABIN7147331)

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TMEM2 Antibody (Biotin)

Binding Specificity: AA 734-866

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell surface hyaluronidase protein (734-866AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMEM2

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Alternative Name: TMEM2

Background:

Background: Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan, not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).

Aliases: KIAA1412 antibody, TMEM 2 antibody, tmem2 antibody, TMEM2_HUMAN antibody, Transmembrane protein 2 antibody

UniProt: Q9UHN6