CP110 antibody (AA 1-280)

Catalog No. ABIN7147358

This Rabbit Polyclonal antibody specifically detects CP110 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CP110 antibody (AA 1-280) (ABIN7147358)

Target: CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CP110 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CP110 Antibody

Binding Specificity: AA 1-280

Purpose: CCP110 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CP110

Target: CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))

Alternative Name: CCP110

Background:

Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

Aliases: 110 kDa centrosomal protein antibody, CCP110 antibody, Centriolar coiled coil protein 110 kDa antibody, Centrosomal protein 110 kDa antibody, Centrosomal protein CP110 antibody, Centrosomal protein of 110 kDa antibody, Cep110 antibody, CP110 antibody, CP110_HUMAN antibody, DKFZp781G1416 antibody, FAN antibody, KIAA0419 antibody

UniProt: O43303

Pathways: M Phase