Centromere Protein X (CENPX) (AA 1-63) antibody

Catalog No. ABIN7147370

This Rabbit Polyclonal antibody specifically detects in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Centromere Protein X (CENPX) (AA 1-63) antibody (ABIN7147370)

Target: Centromere Protein X (CENPX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 1-63

Purpose: CENPX Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Centromere protein X protein (1-63AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Centromere Protein X (CENPX)

Alternative Name: CENPX

Background:

Background: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation.

Aliases: CENP X antibody, CENP-X antibody, CENPX antibody, CENPX_HUMAN antibody, Centromere protein X antibody, FAAP10 antibody, FANCM interacting histone fold protein 2 antibody, FANCM-interacting histone fold protein 2 antibody, Fanconi anemia associated polypeptide of 10 kDa antibody, Fanconi anemia-associated polypeptide of 10 kDa antibody, MGC14480 antibody, Retinoic acid inducible gene D9 protein homolog antibody, Retinoic acid-inducible gene D9 protein homolog antibody, Stimulated by retinoic acid gene 13 protein homolog antibody, STRA13 antibody

UniProt: A8MT69