CCM2 antibody (AA 1-300)

Catalog No. ABIN7147492

This anti-CCM2 antibody is a Rabbit Polyclonal antibody detecting CCM2 in IHC and ELISA. Suitable for Human.

Quick Overview for CCM2 antibody (AA 1-300) (ABIN7147492)

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCM2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-CCM2 Antibody

Binding Specificity: AA 1-300

Purpose: CCM2 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cerebral cavernous malformations 2 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCM2

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Alternative Name: CCM2

Background:

Background: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).

Aliases: C7orf22 antibody, Ccm2 antibody, CCM2 gene antibody, CCM2_HUMAN antibody, Cerebral cavernous malformation 2 antibody, Cerebral cavernous malformations 2 protein antibody, Chromosome 7 open reading frame 22 antibody, Malcavernin antibody, MGC4067 antibody, MGC4607 antibody, MGC74868 antibody, OSM antibody, Osmosensing scaffold for MEKK3 antibody, OTTHUMP00000159554 antibody, OTTHUMP00000214270 antibody, OTTHUMP00000214271 antibody, OTTHUMP00000214273 antibody, PP10187 antibody

UniProt: Q9BSQ5

Pathways: Cell-Cell Junction Organization