Claudin 1 antibody (AA 185-224) (Biotin)

Catalog No. ABIN7147876

This anti-Claudin 1 antibody is a Rabbit Polyclonal antibody detecting Claudin 1 in ELISA. Suitable for Human.

Quick Overview for Claudin 1 antibody (AA 185-224) (Biotin) (ABIN7147876)

Target: Claudin 1 (CLDN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Claudin 1 Antibody (Biotin)

Binding Specificity: AA 185-224

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Claudin-10 protein (185-224AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: CLDN1

Background:

Background: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores, isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle\'s loop in kidney.

Aliases: Claudin-10 antibody, Claudin10 antibody, CLD10_HUMAN antibody, CLDN 10 antibody, CLDN10 antibody, CLDN10 protein antibody, CPETRL 3 antibody, CPETRL3 antibody, HGNC:2033 antibody, OSP L antibody, OSP like protein antibody, OSP-like protein antibody, OSPL antibody

UniProt: P78369

Pathways: Cell-Cell Junction Organization, Hepatitis C