CLASP1 antibody (AA 1389-1538)

Catalog No. ABIN7147935

The Rabbit Polyclonal anti-CLASP1 antibody has been validated for IHC and ELISA. It is suitable to detect CLASP1 in samples from Human.

Quick Overview for CLASP1 antibody (AA 1389-1538) (ABIN7147935)

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLASP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-CLASP1 Antibody

Binding Specificity: AA 1389-1538

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human CLIP-associating protein 1 protein (1389-1538AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CLASP1

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Alternative Name: CLASP1

Background:

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Aliases: 1700030C23Rik antibody, 5730583A19Rik antibody, B130045P17Rik antibody, CLAP1_HUMAN antibody, clasp1 antibody, CLIP associating protein 1 antibody, CLIP associating protein CLASP1 antibody, CLIP-associating protein 1 antibody, Cytoplasmic linker associated protein 1 antibody, Cytoplasmic linker-associated protein 1 antibody, DKFZp686D1968 antibody, DKFZp686H2039 antibody, FLJ33821 antibody, FLJ41222 antibody, hOrbit1 antibody, KIAA0622 antibody, MAST1 antibody, MGC131895 antibody, mKIAA0622 antibody, Multiple asters 1 antibody, Multiple asters homolog 1 antibody, Protein Orbit homolog 1 antibody

UniProt: Q7Z460

Pathways: Microtubule Dynamics, M Phase, Maintenance of Protein Location