COPZ1 antibody (AA 1-177)

Catalog No. ABIN7148022

The Rabbit Polyclonal anti-COPZ1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect COPZ1 in samples from Human.

Quick Overview for COPZ1 antibody (AA 1-177) (ABIN7148022)

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPZ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-COPZ1 Antibody

Binding Specificity: AA 1-177

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Coatomer subunit zeta-1 protein (1-177AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for COPZ1

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Alternative Name: COPZ1

Background:

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Aliases: COPZ1 antibody, COPZ antibody, CGI-120 antibody, HSPC181Coatomer subunit zeta-1 antibody, Zeta-1-coat protein antibody, Zeta-1 COP antibody

UniProt: P61923