Cofilin 2 antibody (AA 1-166)

Catalog No. ABIN7148048

This Rabbit Polyclonal antibody specifically detects Cofilin 2 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Cofilin 2 antibody (AA 1-166) (ABIN7148048)

Target: Cofilin 2 (CFL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Cofilin 2 Antibody

Binding Specificity: AA 1-166

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cofilin-2 protein (1-166AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cofilin 2

Target: Cofilin 2 (CFL2)

Alternative Name: CFL2

Background:

Background: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190). It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity).

Aliases: CFL 2 antibody, CFL2 antibody, COF2_HUMAN antibody, Cofilin 2 muscle antibody, Cofilin antibody, Cofilin muscle antibody, Cofilin muscle isoform antibody, Cofilin-2 antibody, Cofilin2 antibody, muscle isoform antibody, NEM 7 antibody, NEM7 antibody

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis