Aconitase 1 antibody (AA 508-745)

Catalog No. ABIN7149308

This Rabbit Polyclonal antibody specifically detects Aconitase 1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for Aconitase 1 antibody (AA 508-745) (ABIN7149308)

Target: Aconitase 1 (ACO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aconitase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Aconitase 1 Antibody

Binding Specificity: AA 508-745

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cytoplasmic aconitate hydratase protein (508-745AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Aconitase 1

Target: Aconitase 1 (ACO1)

Alternative Name: ACO1

Background:

Background: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

Aliases: ACO 1 antibody, ACO1 antibody, ACOC_HUMAN antibody, Aconitase 1 soluble antibody, Aconitase antibody, Aconitase1 antibody, Aconitate hydratase antibody, ACONS antibody, Citrate hydro lyase antibody, Citrate hydro-lyase antibody, Cytoplasmic aconitate hydratase antibody, Ferritin repressor protein antibody, IRE BP 1 antibody, IRE-BP 1 antibody, IREB 1 antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, Iron regulatory protein 1 antibody, Iron responsive element binding protein 1 antibody, Iron-responsive element-binding protein 1 antibody, IRP 1 antibody, IRP1 antibody, OTTHUMP00000045233 antibody

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis