DYNC1LI1 antibody (AA 167-233) (Biotin)

Catalog No. ABIN7149319

The Biotin-conjugated Rabbit Polyclonal anti-DYNC1LI1 antibody (ABIN7149319) specifically detects DYNC1LI1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for DYNC1LI1 antibody (AA 167-233) (Biotin) (ABIN7149319)

Target: DYNC1LI1 (Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1LI1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-DYNC1LI1 Antibody (Biotin)

Binding Specificity: AA 167-233

Purpose: DYNC1LI1 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 protein (167-233AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DYNC1LI1

Target: DYNC1LI1 (Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1))

Alternative Name: DYNC1LI1

Background:

Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Aliases: Cytoplasmic dynein 1 light intermediate chain 1 antibody, cytosolic antibody, DC1L1_HUMAN antibody, DLC-A antibody, DNCLI1 antibody, dync1li1 antibody, Dynein cytoplasmic 1 light intermediate chain 1 antibody, Dynein cytoplasmic light intermediate polypeptide 1 antibody, Dynein light chain A antibody, Dynein light intermediate chain 1 antibody, Dynein light intermediate chain 1 cytosolic antibody, FLJ10219 antibody, LIC1 antibody

UniProt: Q9Y6G9