CPEB1 antibody (AA 1-486)

Catalog No. ABIN7149336

The Rabbit Polyclonal anti-CPEB1 antibody has been validated for ELISA. It is suitable to detect CPEB1 in samples from Human.

Quick Overview for CPEB1 antibody (AA 1-486) (ABIN7149336)

Target: CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPEB1 antibody is un-conjugated

Application: ELISA

Product Details anti-CPEB1 Antibody

Binding Specificity: AA 1-486

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cytoplasmic polyadenylation element-binding protein 1 protein (1-486AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CPEB1

Target: CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))

Alternative Name: CPEB1

Background:

Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\'-UUUUUAU-3\') within the mRNA 3\'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

Aliases: CEBP antibody, CPE binding protein 1 antibody, CPE BP1 antibody, CPE-binding protein 1 antibody, CPE-BP1 antibody, CPEB 1 antibody, CPEB antibody, CPEB-1 antibody, CPEB1 antibody, CPEB1 protein antibody, CPEB1_HUMAN antibody, Cytoplasmic polyadenylation binding protein 1 antibody, Cytoplasmic polyadenylation element binding protein antibody, Cytoplasmic polyadenylation element binding protein 1 antibody, Cytoplasmic polyadenylation element-binding protein 1 antibody, FLJ13203 antibody, h CEBP antibody, h-CEBP antibody, hCPEB 1 antibody, hCPEB-1 antibody, MGC34136 antibody, MGC60106 antibody, mKIAA0940 antibody, MKIAA0940 protein antibody

UniProt: Q9BZB8

Pathways: Synaptic Membrane