CIAO2A (AA 1-160) antibody

Catalog No. ABIN7149392

This Rabbit Polyclonal antibody specifically detects in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for CIAO2A (AA 1-160) antibody (ABIN7149392)

Target: CIAO2A

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: AA 1-160

Purpose: CIAO2A Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Cytosolic iron-sulfur assembly component 2A protein (1-160AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: CIAO2A

Background:

Background: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227)

Aliases: CIAO2A antibody, CIA2A antibody, FAM96A antibody, Cytosolic iron-sulfur assembly component 2A antibody, MIP18 family protein FAM96A antibody

UniProt: Q9H5X1