CRADD antibody (AA 1-199)

Catalog No. ABIN7149543

Product Details anti-CRADD Antibody

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Binding Specificity: AA 1-199

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRADD antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Death domain-containing protein CRADD protein (1-199AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CRADD

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Alternative Name: CRADD (CRADD Products)

Background:

Background: Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.

Aliases: CASP2 and RIPK1 domain containing adaptor with death domain antibody, Caspase and RIP adapter with death domain antibody, Caspase and RIP adaptor with death domain antibody, Cradd antibody, CRADD_HUMAN antibody, Death adaptor molecule RAIDD antibody, Death domain containing protein CRADD antibody, Death domain-containing protein CRADD antibody, MGC9163 antibody, RIP associated ICH1/CED3 homologous protein with death domain antibody, RIP associated protein with a death domain antibody, RIP-associated protein with a death domain antibody

UniProt: P78560

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity