DHDDS antibody (AA 1-333)

Catalog No. ABIN7149608

This Rabbit Polyclonal antibody specifically detects DHDDS in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DHDDS antibody (AA 1-333) (ABIN7149608)

Target: DHDDS (Dehydrodolichyl Diphosphate Synthase (DHDDS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHDDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DHDDS Antibody

Binding Specificity: AA 1-333

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Dehydrodolichyl diphosphate synthase complex subunit DHDDS protein (1-333AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DHDDS

Target: DHDDS (Dehydrodolichyl Diphosphate Synthase (DHDDS))

Alternative Name: DHDDS

Background:

Background: With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.

Aliases: DHDDS antibody, HDSDehydrodolichyl diphosphate synthase complex subunit DHDDS antibody, EC 2.5.1.87 antibody, Cis-isoprenyltransferase antibody, CIT antibody, Cis-IPTase antibody, Cis-prenyltransferase subunit hCIT antibody, Epididymis tissue protein Li 189m antibody

UniProt: Q86SQ9