DKK3 antibody (AA 22-350) (Biotin)

Catalog No. ABIN7149887

This Rabbit Polyclonal antibody specifically detects DKK3 in ELISA. It exhibits reactivity toward Human.

Quick Overview for DKK3 antibody (AA 22-350) (Biotin) (ABIN7149887)

Target: DKK3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKK3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-DKK3 Antibody (Biotin)

Binding Specificity: AA 22-350

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Dickkopf-related protein 3 protein (22-350AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DKK3

Target: DKK3

Background:

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Aliases: Dickkopf 3 antibody, Dickkopf 3 homolog (Xenopus laevis) antibody, Dickkopf 3 homolog antibody, Dickkopf homolog 3 antibody, Dickkopf related protein 3 antibody, Dickkopf related protein 3 Precursor antibody, Dickkopf WNT signaling pathway inhibitor 3 antibody, Dickkopf, Xenopus, homolog of, 3 antibody, Dickkopf-3 antibody, Dickkopf-related protein 3 antibody, Dickkopf3 antibody, DKK 3 antibody, Dkk-3 antibody, DKK3 antibody, DKK3_HUMAN antibody, hDkk 3 antibody, hDkk-3 antibody, hDkk3 antibody, Regulated in glioma antibody, REIC antibody, RIG antibody, RIG-like 5-6 antibody, RIG-like 7-1 antibody

UniProt: Q9UBP4