POLK antibody (AA 227-337) (FITC)
Quick Overview for POLK antibody (AA 227-337) (FITC) (ABIN7150257)
Target
See all POLK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 227-337
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human DNA polymerase kappa protein (227-337AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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Alternative Name
- POLK
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Background
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Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3\'-5\' proofreading exonuclease activity. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Aliases: DinB homolog 1 (E. coli) antibody, DINB protein antibody, DINB1 antibody, DINP antibody, DNA damage inducible protein b antibody, DNA polymerase kappa antibody, Polk antibody, POLK_HUMAN antibody, POLQ antibody, Polymerase (DNA directed) kappa antibody, polymerase, DNA, kappa antibody
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UniProt
- Q9UBT6
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Pathways
- DNA Damage Repair
Target
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