DAD1 antibody (AA 1-113) (FITC)

Catalog No. ABIN7150601

This Rabbit Polyclonal antibody specifically detects DAD1 in . It exhibits reactivity toward Human.

Quick Overview for DAD1 antibody (AA 1-113) (FITC) (ABIN7150601)

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAD1 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-DAD1 Antibody (FITC)

Binding Specificity: AA 1-113

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DAD1

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Alternative Name: DAD1

Background:

Background: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed:22467853).

Aliases: DAD 1 antibody, DAD-1 antibody, dad1 antibody, DAD1_HUMAN antibody, Defender against cell death 1 antibody, Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, Oligosaccharyl transferase subunit DAD1 antibody, OST 2 antibody, OST2 antibody

UniProt: P61803