STT3A antibody (AA 39-114)

Catalog No. ABIN7150603

The Rabbit Polyclonal anti-STT3A antibody (ABIN7150603) specifically detects STT3A in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for STT3A antibody (AA 39-114) (ABIN7150603)

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STT3A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-STT3A Antibody

Binding Specificity: AA 39-114

Purpose: STT3A Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A protein (39-114AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STT3A

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Alternative Name: STT3A

Background:

Background: Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Aliases: B5 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A antibody, FLJ27038 antibody, Integral membrane protein 1 antibody, Integral transmembrane protein 1 antibody, ITM1 antibody, MGC9042 antibody, Oligosaccharyl transferase subunit STT3A antibody, STT 3A antibody, STT3 subunit of the oligosaccharyltransferase complex homolog A antibody, STT3-A antibody, STT3A antibody, STT3A_HUMAN antibody, TMC antibody, Transmembrane protein TMC antibody

UniProt: P46977