DOC2B antibody (AA 7-180)

Catalog No. ABIN7150615

This anti-DOC2B antibody is a Rabbit Polyclonal antibody detecting DOC2B in ELISA, IHC and IF. Suitable for Human.

Quick Overview for DOC2B antibody (AA 7-180) (ABIN7150615)

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DOC2B Antibody

Binding Specificity: AA 7-180

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DOC2B

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Alternative Name: DOC2B

Background:

Background: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).

Aliases: Doc2 beta antibody, Doc2-beta antibody, Doc2b antibody, DOC2B_HUMAN antibody, DOC2BL antibody, Double C2 like domain containing protein beta antibody, Double C2 like domains beta antibody, Double C2 like domains beta like antibody, Double C2-like domain-containing protein beta antibody, OTTMUSP00000006522 antibody, RP23 78H4.2 antibody

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion