RNF160 antibody (AA 462-591)

Catalog No. ABIN7151049

The Rabbit Polyclonal anti-RNF160 antibody has been validated for ELISA and IHC. It is suitable to detect RNF160 in samples from Human.

Quick Overview for RNF160 antibody (AA 462-591) (ABIN7151049)

Target: RNF160 (ZNF294) (Zinc Finger Protein 294 (ZNF294))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF160 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-RNF160 Antibody

Binding Specificity: AA 462-591

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF160

Target: RNF160 (ZNF294) (Zinc Finger Protein 294 (ZNF294))

Alternative Name: LTN1

Background:

Background: E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).

Aliases: LTN1 antibody, C21orf10 antibody, C21orf98 antibody, KIAA0714 antibody, RNF160 antibody, ZNF294 antibody, HSPC087E3 ubiquitin-protein ligase listerin antibody, EC 2.3.2.27 antibody, RING finger protein 160 antibody, RING-type E3 ubiquitin transferase listerin antibody, Zinc finger protein 294 antibody

UniProt: O94822