Pellino 1 antibody (AA 1-250)

Catalog No. ABIN7151101

This anti-Pellino 1 antibody is a Rabbit Polyclonal antibody detecting Pellino 1 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for Pellino 1 antibody (AA 1-250) (ABIN7151101)

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Pellino 1 Antibody

Binding Specificity: AA 1-250

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase pellino homolog 1 protein (1-250AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Alternative Name: PELI1

Background:

Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates \\\'Lys-63\\\'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.

Aliases: E3 ubiquitin-protein ligase pellino homolog 1 antibody, PELI1 antibody, PELI1_HUMAN antibody, Pellino E3 ubiquitin protein ligase 1 antibody, Pellino homolog 1 antibody, Pellino protein antibody, Pellino-1 antibody, Pellino-related intracellular-signaling molecule antibody, Pellino1 antibody, PRISM antibody, Protein pellino homolog 1 antibody

UniProt: Q96FA3

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades