RNF213 antibody (AA 202-350) (FITC)
Quick Overview for RNF213 antibody (AA 202-350) (FITC) (ABIN7151178)
Target
See all RNF213 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 202-350
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF213 (Ring Finger Protein 213 (RNF213))
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Alternative Name
- RNF213
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Background
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Background: E3 ubiquitin-protein ligase involved in angiogenesis (PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444). Also has ATPase activity (PubMed:24658080, PubMed:26126547).
Aliases: ALK lymphoma oligomerization partner on chromosome 17 antibody, C17orf27 antibody, Chromosome 17 open reading frame 27 antibody, E3 ubiquitin-protein ligase RNF213 antibody, FLJ13051 antibody, KIAA1554 antibody, MGC46622 antibody, MGC9929 antibody, MYMY2 antibody, Mysterin antibody, MYSTR antibody, NET57 antibody, RING finger protein 213 antibody, RN213_HUMAN antibody, RNF 213 antibody, RNF213 antibody
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UniProt
- Q63HN8
Target
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