RNF5 antibody (AA 1-120)

Catalog No. ABIN7151202

Product Details anti-RNF5 Antibody

Target: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Binding Specificity: AA 1-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF5 protein (1-120AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF5

Target: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Alternative Name: RNF5 (RNF5 Products)

Synonyms: 2410131O05Rik antibody, AA407576 antibody, NG2 antibody, RING5 antibody, RMA1 antibody, ring finger protein 5 antibody, Rnf5 antibody, RNF5 antibody

Background:

Background: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the \\\'Lys-63\\\'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the \\\'Lys-48\\\'-linked polyubiquitination of TMEM173 at \\\'Lys-150\\\' leading to its proteasomal degradation, the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses.

Aliases: E3 ubiquitin protein ligase RNF5 antibody, E3 ubiquitin-protein ligase RNF5 antibody, G16 antibody, HsRma1 antibody, NG2 antibody, OTTHUMP00000029107 antibody, Protein G16 antibody, Ram1 homolog antibody, RING finger protein 5 antibody, RING5 antibody, RMA1 antibody, RNF 5 antibody, RNF5 antibody, RNF5_HUMAN antibody

UniProt: Q99942