RNF6 antibody (AA 1-298)

Catalog No. ABIN7151204

This Rabbit Polyclonal antibody specifically detects RNF6 in ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for RNF6 antibody (AA 1-298) (ABIN7151204)

Target: RNF6 (RING Finger Protein 6 (RNF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF6 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-RNF6 Antibody

Binding Specificity: AA 1-298

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF6 protein (1-298AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF6

Target: RNF6 (RING Finger Protein 6 (RNF6))

Alternative Name: RNF6

Background:

Background: E3 ubiquitin-protein ligase mediating \'Lys-48\'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates \'Lys-6\' and \'Lys-27\'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

Aliases: E3 ubiquitin-protein ligase RNF6 antibody, Ring finger protein (C3H2C3 type) 6 antibody, Ring finger protein 6 antibody, RING H2 protein antibody, RING H2 protein RNF6 antibody, RNF 6 antibody, RNF6 antibody, RNF6_HUMAN antibody, SPG2 antibody

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size