UBR1 antibody (AA 722-862) (Biotin)

Catalog No. ABIN7151294

This Rabbit Polyclonal antibody specifically detects UBR1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for UBR1 antibody (AA 722-862) (Biotin) (ABIN7151294)

Target: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBR1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-UBR1 Antibody (Biotin)

Binding Specificity: AA 722-862

Purpose: UBR1 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human E3 ubiquitin-protein ligase UBR1 protein (722-862AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBR1

Target: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Alternative Name: UBR1

Background:

Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Aliases: E3 ubiquitin-protein ligase UBR1 antibody, JBS antibody, N-recognin-1 antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, Ubiquitin-protein ligase E3-alpha-1 antibody, Ubiquitin-protein ligase E3-alpha-I antibody, UBR1 antibody, UBR1_HUMAN antibody

UniProt: Q8IWV7