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Emerin antibody (AA 1-222)

This Rabbit Polyclonal antibody specifically detects Emerin in WB, ELISA, IHC, IF and IP. It exhibits reactivity toward Human.
Catalog No. ABIN7151606

Quick Overview for Emerin antibody (AA 1-222) (ABIN7151606)

Target

See all Emerin (EMD) Antibodies
Emerin (EMD)

Reactivity

  • 82
  • 17
  • 14
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 50
  • 32
  • 2
Rabbit

Clonality

  • 49
  • 35
Polyclonal

Conjugate

  • 41
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Emerin antibody is un-conjugated

Application

  • 70
  • 33
  • 27
  • 20
  • 15
  • 13
  • 13
  • 8
  • 8
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • Binding Specificity

    • 24
    • 15
    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-222

    Cross-Reactivity

    Human, Mouse

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Human Emerin protein (1-222AA)

    Isotype

    IgG
  • Application Notes

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Emerin (EMD)

    Alternative Name

    EMD

    Background

    Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

    Aliases: EDMD antibody, Emd antibody, EMD_HUMAN antibody, Emerin antibody, Emery Dreifuss muscular dystrophy antibody, STA antibody

    UniProt

    P50402
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