ESRP2 antibody (AA 615-720) (Biotin)

Catalog No. ABIN7151938

This anti-ESRP2 antibody is a Rabbit Polyclonal antibody detecting ESRP2 in ELISA. Suitable for Human.

Quick Overview for ESRP2 antibody (AA 615-720) (Biotin) (ABIN7151938)

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRP2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-ESRP2 Antibody (Biotin)

Binding Specificity: AA 615-720

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Epithelial splicing regulatory protein 2 protein (615-720AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Alternative Name: ESRP2

Background:

Background: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Aliases: Epithelial splicing regulatory protein 2 antibody, ESRP 2 antibody, ESRP2 antibody, ESRP2_HUMAN antibody, FLJ21918 antibody, FLJ22248 antibody, RBM35B antibody, RNA binding motif protein 35A antibody, RNA binding motif protein 35B antibody, RNA binding protein 35B antibody, RNA-binding motif protein 35B antibody, RNA-binding protein 35B antibody

UniProt: Q9H6T0