Elf4 antibody (AA 1-200)

Catalog No. ABIN7152098

This Rabbit Polyclonal antibody specifically detects Elf4 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Elf4 antibody (AA 1-200) (ABIN7152098)

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Elf4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Elf4 Antibody

Binding Specificity: AA 1-200

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Alternative Name: ELF4

Background:

Background: Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.

Aliases: E74-like factor 4 antibody, ELF4 antibody, ELF4_HUMAN antibody, ELFR antibody, ETS-related transcription factor Elf-4 antibody, ETS-related transcription factor Elf4 antibody, MEF antibody, Myeloid Elf-1-like factor antibody, Myeloid Elf1-like factor antibody

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity