FCHO2 antibody (AA 100-203)
Quick Overview for FCHO2 antibody (AA 100-203) (ABIN7152394)
Target
See all FCHO2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-203
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Cross-Reactivity
- Human, Mouse
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human F-BAR domain only protein 2 protein (100-203AA)
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Isotype
- IgG
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anti-FCH Domain Only 2 (FCHO2) (AA 137-165) antibody
FCHO2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB28095 unconjugated
anti-FCH Domain Only 2 (FCHO2) (Middle Region) antibodyFCHO2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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Application Notes
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FCHO2 (FCH Domain Only 2 (FCHO2))
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Alternative Name
- FCHO2
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Background
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Background: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
Aliases: FCHO2F-BAR domain only protein 2 antibody
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UniProt
- Q0JRZ9
Target
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