Cyclin F antibody (AA 248-400)

Catalog No. ABIN7152402

The Rabbit Polyclonal anti-Cyclin F antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect Cyclin F in samples from Human.

Quick Overview for Cyclin F antibody (AA 248-400) (ABIN7152402)

Target: Cyclin F (CCNF)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin F antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Cyclin F Antibody

Binding Specificity: AA 248-400

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human F-box only protein 10 protein (248-400AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cyclin F

Target: Cyclin F (CCNF)

Alternative Name: FBXO1

Background:

Background: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.

Aliases: F box protein 10 antibody, F-box only protein 10 antibody, FBX10 antibody, FBX10_HUMAN antibody, Fbxo10 antibody, hCG_2011110 antibody, PRMT11 antibody

UniProt: Q9UK96