FBXO10 antibody (Middle Region)

Catalog No. ABIN2785925

This Rabbit Polyclonal antibody specifically detects FBXO10 in WB. It exhibits reactivity toward Human, Dog, Horse, Guinea Pig and Rat.

Quick Overview for FBXO10 antibody (Middle Region) (ABIN2785925)

Target: FBXO10 (F-Box Protein 10 (FBXO10))

Reactivity: Human, Dog, Horse, Guinea Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO10 Antibody

Binding Specificity: Middle Region

Purpose: FBXO10 Antibody - middle region

Sequence: SSSPKPGSKA GSQEAEVGSD GERVAQTPDS SDGGLSPSGE DEDEDQLMYR

Predicted Reactivity: Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against FBXO10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54857-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO10

Target: FBXO10 (F-Box Protein 10 (FBXO10))

Alternative Name: FBXO10

Background:

Background Information: Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Gene Name: F-box protein 10

Alternative Symbols: FBX10, PRMT11

Protein Name: F-box only protein 10

Molecular Weight: 105kDa

Gene ID: 26267

NCBI Accession: NP_036298

UniProt: Q9UK96