FBXW10 antibody (AA 701-1000)

Catalog No. ABIN7152486

The Rabbit Polyclonal anti-FBXW10 antibody is suitable to detect FBXW10 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for FBXW10 antibody (AA 701-1000) (ABIN7152486)

Target: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW10 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FBXW10 Antibody

Binding Specificity: AA 701-1000

Purpose: FBXW10 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FBXW10

Target: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Alternative Name: FBXW10

Background:

Background: Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.

Aliases: FBXW10 antibody, F-box/WD repeat-containing protein 10 antibody, F-box and WD-40 domain-containing protein 10 antibody, Ubiquitin ligase-specificity factor antibody

UniProt: Q5XX13