C1orf86 antibody (AA 14-179) (Biotin)

Catalog No. ABIN7152533

This Rabbit Polyclonal antibody specifically detects C1orf86 in ELISA. It exhibits reactivity toward Human.

Quick Overview for C1orf86 antibody (AA 14-179) (Biotin) (ABIN7152533)

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf86 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-C1orf86 Antibody (Biotin)

Binding Specificity: AA 14-179

Purpose: FAAP20 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Fanconi anemia core complex-associated protein 20 protein (14-179AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C1orf86

Target: C1orf86 (C1ORF86) (Chromosome 1 Open Reading Frame 86 (C1ORF86))

Alternative Name: FAAP20

Background:

Background: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds \'Lys-63\'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.

Aliases: C1orf86 antibody, CA086_HUMAN antibody, Chromosome 1 open reading frame 86 antibody, FAAP20 antibody, Fanconi anemia associated protein of 20 kDa antibody, FP7162 antibody, RP11-181G12.3 antibody, Uncharacterized protein C1orf86 antibody

UniProt: Q6NZ36