Filamin A antibody (AA 1234-1462) (HRP)

Catalog No. ABIN7152947

This Rabbit Polyclonal antibody specifically detects Filamin A in ELISA. It exhibits reactivity toward Human.

Quick Overview for Filamin A antibody (AA 1234-1462) (HRP) (ABIN7152947)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is conjugated to HRP

Application: ELISA

Product Details anti-Filamin A Antibody (HRP)

Binding Specificity: AA 1234-1462

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Filamin-A protein (1234-1462AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: FLNA

Background:

Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

Aliases: ABP 280 antibody, ABP-280 antibody, Actin-binding protein 280 antibody, Alpha filamin antibody, Alpha-filamin antibody, APBX antibody, CSBS antibody, CVD1 antibody, Endothelial actin binding protein antibody, Endothelial actin-binding protein antibody, Filamin 1 antibody, Filamin A alpha antibody, Filamin A antibody, Filamin-1 antibody, Filamin-A antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FLNA antibody, FLNA_HUMAN antibody, FMD antibody, MNS antibody, NHBP antibody, Non muscle filamin antibody, Non-muscle filamin antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location