MIOS antibody (AA 1-237)

Catalog No. ABIN7153697

This Rabbit Polyclonal antibody specifically detects MIOS in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for MIOS antibody (AA 1-237) (ABIN7153697)

Target: MIOS (WD Repeat-Containing Protein Mio (MIOS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIOS antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MIOS Antibody

Binding Specificity: AA 1-237

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human GATOR complex protein MIOS protein (1-237AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MIOS

Target: MIOS (WD Repeat-Containing Protein Mio (MIOS))

Alternative Name: MIOS

Background:

Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

Aliases: MIOS antibody, GATOR complex protein MIOS antibody, Missing oocyte meiosis regulator homolog antibody

UniProt: Q9NXC5