Gelsolin antibody (AA 28-782)

Catalog No. ABIN7153749

The Rabbit Polyclonal anti-Gelsolin antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect Gelsolin in samples from Human.

Quick Overview for Gelsolin antibody (AA 28-782) (ABIN7153749)

Target: Gelsolin (GSN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Gelsolin Antibody

Binding Specificity: AA 28-782

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Gelsolin protein (28-782AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background:

Background: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Aliases: Actin depolymerizing factor antibody, Actin-depolymerizing factor antibody, ADF antibody, AGEL antibody, Brevin antibody, DKFZp313L0718 antibody, GELS_HUMAN antibody, Gelsolin antibody, Gsn antibody

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy