Glutamate Receptor 3 antibody (AA 151-250)

Catalog No. ABIN7153961

This Rabbit Polyclonal antibody specifically detects Glutamate Receptor 3 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Glutamate Receptor 3 antibody (AA 151-250) (ABIN7153961)

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Glutamate Receptor 3 Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutamate receptor 3 protein (151-250AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3

Background:

Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Aliases: AMPA 3 antibody, AMPA selective glutamate receptor 3 antibody, AMPA-selective glutamate receptor 3 antibody, dJ1171F9.1 antibody, GluA3 antibody, GLUK3 antibody, GluR 3 antibody, GLUR C antibody, GLUR K3 antibody, GluR-3 antibody, GluR-C antibody, GluR-K3 antibody, GLUR3 antibody, GLURC antibody, Glutamate ionotropic receptor AMPA type subunit 3 antibody, Glutamate receptor 3 antibody, Glutamate receptor C antibody, Glutamate receptor ionotrophic AMPA 3 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor subunit 3 antibody, Glutamate receptor, ionotropic, AMPA 3 antibody, GRIA 3 antibody, Gria3 antibody, GRIA3_HUMAN antibody, Ionotrophic Glutamate Receptor antibody, MRX94 antibody

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane