GCLC antibody (Catalytic Subunit)

Catalog No. ABIN7153998

The Rabbit Polyclonal anti-GCLC antibody is suitable to detect GCLC in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for GCLC antibody (Catalytic Subunit) (ABIN7153998)

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCLC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-GCLC Antibody

Binding Specificity: AA 78-236, Catalytic Subunit

Purpose: GCLC Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Glutamate--cysteine ligase catalytic subunit protein (78-236AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GCLC

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Alternative Name: GCLC

Background:

Background: cytosol, glutamate-cysteine ligase complex, ADP binding, coenzyme binding, glutamate binding, glutamate-cysteine ligase activity, magnesium ion binding, cell redox homeostasis, cysteine metabolic process, glutamate metabolic process

Aliases: EC 6.3.2.2 antibody, Gamma ECS antibody, Gamma glutamylcysteine synthetase antibody, Gamma-ECS antibody, Gamma-glutamylcysteine synthetase antibody, GCL antibody, Gclc antibody, GCS antibody, GCS heavy chain antibody, GLCL antibody, GLCLC antibody, Glutamate cysteine ligase catalytic subunit antibody, Glutamate--cysteine ligase catalytic subunit antibody, GSH1_HUMAN antibody

UniProt: P48506

Pathways: Cell RedoxHomeostasis