GGT1 antibody (AA 13-225) (Biotin)

Catalog No. ABIN7154061

The Rabbit Polyclonal anti-GGT1 antibody has been validated for ELISA. It is suitable to detect GGT1 in samples from Human.

Quick Overview for GGT1 antibody (AA 13-225) (Biotin) (ABIN7154061)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGT1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-GGT1 Antibody (Biotin)

Binding Specificity: AA 13-225

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutathione hydrolase 1 proenzyme protein (13-225AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1

Background:

Background: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

Aliases: CD224 antibody, D22S672 antibody, D22S732 antibody, Gamma glutamyl transpeptidase antibody, Gamma glutamyltransferase 1 antibody, Gamma glutamyltranspeptidase 1 antibody, Gamma-glutamyltransferase 1 antibody, Gamma-glutamyltranspeptidase 1 light chain antibody, GGT 1 antibody, GGT antibody, GGT1 antibody, GGT1_HUMAN antibody, Glutamyl transpeptidase antibody, Glutathione hydrolase 1 antibody, GTG antibody, Leukotriene C4 hydrolase antibody, MGC96892 antibody, MGC96904 antibody, MGC96963 antibody, OTTHUMP00000028921 antibody, OTTHUMP00000197959 antibody

UniProt: P19440