GAB2 antibody (AA 273-484) (Biotin)

Catalog No. ABIN7154437

This anti-GAB2 antibody is a Rabbit Polyclonal antibody detecting GAB2 in ELISA. Suitable for Human.

Quick Overview for GAB2 antibody (AA 273-484) (Biotin) (ABIN7154437)

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-GAB2 Antibody (Biotin)

Binding Specificity: AA 273-484

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human GRB2-associated-binding protein 2 protein (273-484AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GAB2

Target: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Alternative Name: GAB2

Background:

Background: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

Aliases: GAB 2 antibody, Gab2 antibody, GAB2_HUMAN antibody, Grb 2 associated binder 2 antibody, GRB 2 associated binding protein 2 antibody, Grb2 associated binder 2 antibody, GRB2 associated binder 2 pp100 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binder 2 antibody, GRB2-associated-binding protein 2 antibody, Growth factor receptor bound protein 2 associated protein 2 antibody, Growth factor receptor bound protein 2-associated protein 2 antibody, KIAA0571 antibody, p97 antibody, PH domain containing adaptor molecule p97 antibody, pp100 antibody

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect