TRAP1 antibody (AA 60-308) (Biotin)

Catalog No. ABIN7154904

The Rabbit Polyclonal anti-TRAP1 antibody has been validated for ELISA. It is suitable to detect TRAP1 in samples from Human.

Quick Overview for TRAP1 antibody (AA 60-308) (Biotin) (ABIN7154904)

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAP1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TRAP1 Antibody (Biotin)

Binding Specificity: AA 60-308

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Heat shock protein 75 kDa, mitochondrial protein (60-308AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRAP1

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Alternative Name: TRAP1

Background:

Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Aliases: Heat shock protein 75 kDa antibody, Heat shock protein 75 kDa, mitochondrial antibody, HSP 75 antibody, HSP75 antibody, HSP90L antibody, mitochondrial antibody, TNF receptor associated protein 1 antibody, TNFR-associated protein 1 antibody, TRAP-1 antibody, Trap1 antibody, TRAP1_HUMAN antibody, Tumor necrosis factor type 1 receptor-associated protein antibody

UniProt: Q12931