CENPA antibody (AA 1-50) (HRP)

Catalog No. ABIN7155422

This Rabbit Polyclonal antibody specifically detects CENPA in ELISA. It exhibits reactivity toward Human.

Quick Overview for CENPA antibody (AA 1-50) (HRP) (ABIN7155422)

Target: CENPA (Centromere Protein A (CENPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPA antibody is conjugated to HRP

Application: ELISA

Product Details anti-CENPA Antibody (HRP)

Binding Specificity: AA 1-50

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone H3-like centromeric protein A protein (1-50AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CENPA

Target: CENPA (Centromere Protein A (CENPA))

Alternative Name: CENPA

Background:

Background: Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).

Aliases: CENP A antibody, CENP-A antibody, cenpa antibody, CENPA_HUMAN antibody, Centromere autoantigen A antibody, Centromere protein A 17 kDa antibody, Centromere protein A antibody, Histone H3 like centromeric protein A antibody, Histone H3-like centromeric protein A antibody

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location