SUV420H1 antibody (AA 100-150) (HRP)

Catalog No. ABIN7155484

This anti-SUV420H1 antibody is a Rabbit Polyclonal antibody detecting SUV420H1 in ELISA. Suitable for Human.

Quick Overview for SUV420H1 antibody (AA 100-150) (HRP) (ABIN7155484)

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUV420H1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-SUV420H1 Antibody (HRP)

Binding Specificity: AA 100-150

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone-lysine N-methyltransferase KMT5B protein (100-150AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUV420H1

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Alternative Name: KMT5B

Background:

Background: Histone methyltransferase that specifically trimethylates \'Lys-20\' of histone H4. H4 \'Lys-20\' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.

Aliases: CGI 85 antibody, CGI85 antibody, Histone-lysine N-methyltransferase KMT5B antibody, Kmt5b antibody, KMT5B_HUMAN antibody, Lysine N-methyltransferase 5B antibody, Lysine-specific methyltransferase 5B antibody, MGC118906 antibody, MGC118909 antibody, MGC21161 antibody, MGC703 antibody, Su(var)4-20 homolog 1 antibody, Suppressor of variegation 4 20 homolog 1 antibody, Suppressor of variegation 4-20 homolog 1 antibody, Suv4-20h1 antibody

UniProt: Q4FZB7