OCRL antibody (AA 121-271) (Biotin)

Catalog No. ABIN7156317

The Rabbit Polyclonal anti-OCRL antibody has been validated for ELISA. It is suitable to detect OCRL in samples from Human.

Quick Overview for OCRL antibody (AA 121-271) (Biotin) (ABIN7156317)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCRL antibody is conjugated to Biotin

Application: ELISA

Product Details anti-OCRL Antibody (Biotin)

Binding Specificity: AA 121-271

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Inositol polyphosphate 5-phosphatase OCRL-1 protein (121-271AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: OCRL

Background:

Background: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).

Aliases: EC 3.1.3.36 antibody, Inositol polyphosphate 5 phosphatase OCRL 1 antibody, Inositol polyphosphate 5 phosphatase OCRL1 antibody, Inositol polyphosphate 5-phosphatase OCRL-1 antibody, INPP5F antibody, LOCR antibody, Lowe oculocerebrorenal syndrome protein antibody, NPHL2 antibody, OCRL 1 antibody, OCRL antibody, OCRL_HUMAN antibody, OCRL1 antibody, Oculocerebrorenal syndrome of Lowe antibody, Phosphatidylinositol polyphosphate 5 phosphatase antibody

UniProt: Q01968

Pathways: Inositol Metabolic Process